Basic Information
ID: ALA4042554
Type: ADME
Description: Binding affinity to human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated for 3 mins followed by addition of GABA measured after 3 mins by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4042554
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.39 | 2.78 | 2.78 |
| 373.39 | 3.52 | 3.52 |
| 355.40 | 3.38 | 3.38 |
| 328.33 | 2.30 | 2.30 |
| 351.37 | 3.25 | 3.25 |
| 380.41 | 3.21 | 3.21 |
| 358.40 | 2.78 | 2.78 |
| 368.37 | 4.00 | 4.00 |
| 350.38 | 3.86 | 3.86 |
| 366.38 | 2.96 | 2.96 |