Basic Information
ID: ALA4042561
Type: ADME
Description: Drug metabolism in Sprague-Dawley rat brain assessed as (E)-8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid formation at 10 mg/kg, po measured after 120 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain
Activity Charts
Bioactivity
Activity Types for Assay ALA4042561
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.39 | 2.78 | 2.78 |
| 328.33 | 2.30 | 2.30 |
| 351.37 | 3.25 | 3.25 |
| 380.41 | 3.21 | 3.21 |
| 358.40 | 2.78 | 2.78 |