Basic Information
ID: ALA4042623
Type: Binding
Description: Inhibition of quorum sensing LasI synthase in Pseudomonas aeruginosa PAO1 harboring reporter plasmid lasB-gfp assessed as reduction in lasB expression measured every 15 mins for 12 hrs by GFP-fluorescence assay
Organism: Pseudomonas aeruginosa PAO1
Activity Charts
Bioactivity
Activity Types for Assay ALA4042623
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.41 | 3.00 | 3.00 |
| 261.30 | 1.81 | 1.81 |
| 332.50 | 5.71 | 5.71 |
| 281.47 | 5.37 | 5.37 |
| 420.61 | 6.50 | 6.50 |
| 241.41 | 4.45 | 4.45 |
| 468.49 | 7.74 | 7.74 |
| 323.90 | 6.06 | 6.06 |
| 377.87 | 6.77 | 6.77 |
| 163.27 | 0.86 | 0.86 |
| 353.92 | 6.15 | 6.15 |
| 205.33 | 2.05 | 2.05 |
| 277.80 | 5.10 | 5.10 |
| 196.34 | 3.75 | 3.75 |
| 209.34 | 3.80 | 3.80 |
| 161.25 | 1.56 | 1.56 |
| 221.35 | 3.96 | 3.96 |
| 344.31 | 6.40 | 6.40 |
| 253.42 | 4.53 | 4.53 |
| 360.55 | 6.32 | 6.32 |
| 207.32 | 3.57 | 3.57 |
| 309.87 | 5.75 | 5.75 |
| 305.45 | 5.10 | 5.10 |
| 273.84 | 4.88 | 4.88 |
| 253.35 | 3.76 | 3.76 |
| 257.77 | 4.41 | 4.41 |
| 239.39 | 4.22 | 4.22 |
| 283.44 | 4.62 | 4.62 |
| 307.39 | 5.24 | 5.24 |
| 275.42 | 5.10 | 5.10 |