Basic Information
ID: ALA4042639
Type: Binding
Description: Inhibition of human PRC2-EED (76 to 441 residues) expressed in Escherichia coli BL21 (DE3) using histone H3[21 to 44, K27MeO] as substrate and SAM as co-factor measured after 2 hrs by LC-MS/MS method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4042639
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 175.28 | 2.23 | 2.23 |
| 223.29 | 2.38 | 2.38 |
| 271.32 | 2.00 | 2.00 |
| 219.28 | 1.96 | 1.96 |
| 267.33 | 3.02 | 3.02 |
| 287.38 | 3.53 | 3.53 |
| 215.30 | 2.97 | 2.97 |
| 205.30 | 2.24 | 2.24 |
| 257.34 | 2.58 | 2.58 |
| 215.30 | 2.97 | 2.97 |
| 258.32 | 2.77 | 2.77 |
| 205.30 | 2.24 | 2.24 |
| 317.41 | 3.54 | 3.54 |
| 247.34 | 1.84 | 1.84 |
| 257.34 | 2.58 | 2.58 |
| 351.49 | 3.98 | 3.98 |
| 313.40 | 3.44 | 3.44 |
| 205.30 | 2.24 | 2.24 |
| 261.32 | 1.56 | 1.56 |