Basic Information
ID: ALA4042827
Type: ADME
Description: Drug metabolism in pH 7.4 PBS assessed as rat P450 oxidoreductase-mediated compound hydrolysis preincubated for 20 mins followed by protocatechuate 3,4-dioxygenase addition to create anoxic condition and subsequent addition of P450 oxidoreductase in presence of NADPH after 24 hrs by HPLC method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4042827
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.46 | 4.77 | 4.77 |
| 481.50 | 5.17 | 5.17 |
| 487.53 | 5.24 | 5.24 |