Basic Information
ID: ALA4042997
Type: Binding
Description: Inhibition of recombinant human full length His-tagged Bcr-Abl fusion protein cytoplasmic domain expressed in baculovirus expression system using tyrosine-2 as substrate measured after 1 hr by FRET-based Z'-Lyte assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Bcr/Abl fusion protein(ALA2096618)
Document: ALA4041549
Inhibition of recombinant human full length His-tagged Bcr-Abl fusion protein cytoplasmic domain expressed in baculovirus expression system using tyrosine-2 as substrate measured after 1 hr by FRET-based Z'-Lyte assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4042997
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.62 | 5.01 | 5.01 |
| 524.59 | 4.62 | 4.62 |
| 510.56 | 4.62 | 4.62 |
| 524.59 | 4.62 | 4.62 |
| 484.65 | 4.16 | 4.16 |
| 496.66 | 4.48 | 4.48 |
| 524.59 | 4.62 | 4.62 |
| 527.62 | 5.42 | 5.42 |
| 538.62 | 4.79 | 4.79 |
| 538.62 | 5.01 | 5.01 |
| 495.55 | 5.47 | 5.47 |
| 532.69 | 5.27 | 5.27 |
| 538.62 | 5.01 | 5.01 |
| 512.70 | 4.90 | 4.90 |
| 545.61 | 5.32 | 5.32 |
| 511.55 | 4.70 | 4.70 |
| 524.59 | 4.05 | 4.05 |
| 538.74 | 5.65 | 5.65 |
| 456.59 | 3.60 | 3.60 |
| 412.42 | 4.87 | 4.87 |
| 469.51 | 4.93 | 4.93 |
| 524.59 | 4.62 | 4.62 |
| 509.58 | 5.86 | 5.86 |
| 524.59 | 4.62 | 4.62 |
| 524.59 | 4.62 | 4.62 |
| 498.68 | 4.72 | 4.72 |
| 510.56 | 4.06 | 4.06 |
| 524.59 | 4.45 | 4.45 |
| 538.62 | 4.66 | 4.66 |
| 592.71 | 6.32 | 6.32 |
| 538.62 | 5.01 | 5.01 |
| 539.61 | 5.01 | 5.01 |
| 510.56 | 4.06 | 4.06 |