Inhibition of BACE1 (unknown origin) at 10 uM pre-incubated for 10 mins before addition of fluorescent substrate HiLyte FluorTM 488-Glu-Val-Asn-Leu-As...

Basic Information

ID: ALA4043661

Type: Binding

Description: Inhibition of BACE1 (unknown origin) at 10 uM pre-incubated for 10 mins before addition of fluorescent substrate HiLyte FluorTM 488-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys and measured over 30 mins

Format: BAO_0000357

Organism: Homo sapiens

Target: Beta-secretase 1(ALA4822)

Document: ALA4043083

Inhibition of BACE1 (unknown origin) at 10 uM pre-incubated for 10 mins before addition of fluorescent substrate HiLyte FluorTM 488-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys and measured over 30 mins: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4043661

Inhibition

Total(21)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
496.61	4.70	4.70
286.33	0.36	0.36
390.44	1.50	1.50
330.38	1.15	1.15
362.43	0.66	0.66
368.43	0.54	0.54
362.43	0.66	0.66
362.43	0.66	0.66
388.42	0.87	0.87
362.43	0.66	0.66
509.63	2.85	2.85
438.55	2.41	2.41
348.42	0.80	0.80
420.51	2.76	2.76
383.47	2.72	2.72
408.45	1.52	1.52
419.50	1.24	1.24
293.34	1.11	1.11
383.47	2.72	2.72
438.55	2.41	2.41
509.63	2.85	2.85