Basic Information
ID: ALA4043763
Type: Functional
Description: Neuroprotective activity against fibril amyloid beta (25 to 35)-induced cell death in Sprague-Dawley rat 5 days old neonatal primary cortical neurons assessed as increase in cell viability pretreated for 2 hrs followed by 10 uM fibril amyloid beta (25 to 35) addition measured after 48 hrs by MTT assay
Format: BAO_0000219
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Cell type: Cortical neurone
Target: Cortical neurone(ALA5314313)
Document: ALA4043092
Neuroprotective activity against fibril amyloid beta (25 to 35)-induced cell death in Sprague-Dawley rat 5 days old neonatal primary cortical neurons assessed as increase in cell viability pretreated for 2 hrs followed by 10 uM fibril amyloid beta (25 to 35) addition measured after 48 hrs by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4043763
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.28 | 3.18 | 3.18 |
| 321.13 | 3.98 | 3.98 |
| 321.13 | 3.98 | 3.98 |
| 321.13 | 3.98 | 3.98 |
| 356.33 | 3.50 | 3.50 |
| 340.33 | 3.79 | 3.79 |
| 326.35 | 3.55 | 3.55 |
| 368.39 | 3.88 | 3.88 |
| 324.33 | 4.09 | 4.09 |
| 314.34 | 3.40 | 3.40 |
| 326.35 | 3.55 | 3.55 |
| 326.30 | 3.27 | 3.27 |
| 349.18 | 4.06 | 4.06 |