ID: ALA4043789
Type: Binding
Description: Inhibition of FGFR2 in human FGFR2-amplified SUM52 cells assessed as decrease in FGF-induced phosphorylated ERK1/2 expression levels at 100 nM preincubated for 30 mins followed by compound washout and incubated under drug free condition for 120 mins and subsequent FGF stimulation measured after 15 mins by Western blot analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4043789
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
523.68 | 5.16 | 5.16 |
656.62 | 6.61 | 6.61 |
640.57 | 5.60 | 5.60 |