Basic Information
ID: ALA4043790
Type: Binding
Description: Inhibition of FGFR3 in human FGFR3-amplified SW780 cells assessed as decrease in FGF-induced phosphorylated ERK1/2 expression levels at 100 nM pretreated for 30 mins followed by FGF stimulation measured after 15 mins by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4043790
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.68 | 5.16 | 5.16 |
| 656.62 | 6.61 | 6.61 |
| 640.57 | 5.60 | 5.60 |