Assay Report Card

Basic Information

ID: ALA4043791

Type: Binding

Description: Inhibition of FGFR3 in human FGFR3-amplified SW780 cells assessed as decrease in FGF-induced phosphorylated ERK1/2 expression levels at 100 nM preincubated for 30 mins followed by compound washout and incubated under drug free condition for 120 mins and subsequent FGF stimulation measured after 15 mins by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
523.685.165.16
656.626.616.61
640.575.605.60