Basic Information
ID: ALA4044270
Type: Binding
Description: Inhibition of FGFR2 in human FGFR2-amplified SUM52 cells assessed as decrease in FGF-induced FGFR2 phosphorylated expression levels at 100 nM preincubated for 30 mins followed by compound washout and incubated under drug free condition for 120 mins and subsequent FGF stimulation measured after 15 mins by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4044270
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.68 | 5.16 | 5.16 |
| 656.62 | 6.61 | 6.61 |
| 640.57 | 5.60 | 5.60 |