Basic Information
ID: ALA4044420
Type: Functional
Description: Antagonist activity at human GPR4 expressed in human HeLa cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cAMP addition measured after 60 mins by HTRF method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: G-protein coupled receptor 4(ALA3638324)
Document: ALA4043105
Antagonist activity at human GPR4 expressed in human HeLa cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cAMP addition measured after 60 mins by HTRF method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4044420
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.63 | 4.70 | 4.70 |
| 425.62 | 4.22 | 4.22 |
| 417.60 | 4.44 | 4.44 |
| 445.66 | 5.09 | 5.09 |
| 454.06 | 4.56 | 4.56 |
| 504.77 | 5.56 | 5.56 |
| 496.14 | 6.15 | 6.15 |
| 449.64 | 3.92 | 3.92 |
| 431.63 | 4.70 | 4.70 |
| 445.66 | 5.26 | 5.26 |
| 529.70 | 6.51 | 6.51 |
| 444.63 | 3.78 | 3.78 |
| 425.62 | 4.82 | 4.82 |
| 486.71 | 5.36 | 5.36 |
| 475.73 | 5.80 | 5.80 |
| 449.69 | 5.19 | 5.19 |
| 447.67 | 4.52 | 4.52 |
| 403.57 | 4.08 | 4.08 |
| 491.72 | 5.50 | 5.50 |
| 459.68 | 5.33 | 5.33 |
| 477.66 | 3.73 | 3.73 |
| 489.75 | 6.11 | 6.11 |