Basic Information
ID: ALA4044422
Type: Functional
Description: Antagonist activity at rat GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cAMP addition measured after 60 mins by HTRF method
Format: BAO_0000219
Organism: Rattus norvegicus
Target: G-protein coupled receptor 4(ALA4105950)
Document: ALA4043105
Antagonist activity at rat GPR4 expressed in HEK cells assessed as inhibition of pH-induced cAMP accumulation preincubated for 15 mins followed by cAMP addition measured after 60 mins by HTRF method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4044422
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.63 | 4.70 | 4.70 |
| 425.62 | 4.22 | 4.22 |
| 417.60 | 4.44 | 4.44 |
| 445.66 | 5.09 | 5.09 |
| 431.63 | 4.70 | 4.70 |
| 445.66 | 5.26 | 5.26 |
| 425.62 | 4.82 | 4.82 |
| 449.69 | 5.19 | 5.19 |
| 403.57 | 4.08 | 4.08 |
| 459.68 | 5.33 | 5.33 |
| 477.66 | 3.73 | 3.73 |