Basic Information
ID: ALA4044802
Type: ADME
Description: Inhibition of COX-1 in rat peritoneal macrophages assessed as reduction in [125I]-6-Keto-PGF1alpha production using arachidonic acid as substrate pretreated for 30 mins followed by substrate addition measured after 30 mins
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4044802
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 332.43 | 1.52 | 1.52 |
| 333.41 | 1.95 | 1.95 |
| 437.74 | 2.86 | 2.86 |
| 387.39 | 1.62 | 1.62 |
| 349.48 | 2.66 | 2.66 |
| 453.80 | 3.57 | 3.57 |
| 333.42 | 1.08 | 1.08 |
| 403.45 | 3.21 | 3.21 |
| 388.37 | 2.05 | 2.05 |
| 435.76 | 2.87 | 2.87 |
| 334.40 | 1.51 | 1.51 |
| 436.75 | 3.30 | 3.30 |
| 386.40 | 2.06 | 2.06 |
| 350.47 | 2.22 | 2.22 |
| 452.82 | 4.01 | 4.01 |
| 387.38 | 2.49 | 2.49 |
| 436.75 | 2.43 | 2.43 |
| 404.44 | 2.76 | 2.76 |