Basic Information
ID: ALA4046304
Type: ADME
Description: Apparent permeability in MDCK2-MDR1 cells at 3 uM incubated for 1 hr in presence of P-glycoprotein inhibitor GF120918 by LC/MS/MS method
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA4046304
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.40 | -1.53 | -1.53 |
| 363.42 | -1.22 | -1.22 |
| 377.45 | -1.04 | -1.04 |
| 381.41 | -1.19 | -1.19 |
| 374.45 | 0.69 | 0.69 |
| 403.49 | 0.73 | 0.73 |
| 529.64 | 2.68 | 2.68 |
| 391.48 | -0.29 | -0.29 |
| 503.56 | 0.57 | 0.57 |
| 435.49 | -0.43 | -0.43 |
| 489.53 | 0.18 | 0.18 |
| 391.43 | -1.35 | -1.35 |
| 421.48 | 0.61 | 0.61 |
| 363.42 | -1.07 | -1.07 |
| 405.46 | -0.96 | -0.96 |
| 503.60 | 2.15 | 2.15 |
| 497.56 | 0.75 | 0.75 |
| 433.51 | -0.06 | -0.06 |
| 389.46 | -0.68 | -0.68 |
| 529.69 | 3.38 | 3.38 |
| 389.46 | 0.27 | 0.27 |
| 378.43 | -0.71 | -0.71 |
| 429.53 | 1.11 | 1.11 |
| 475.51 | -0.21 | -0.21 |
| 419.49 | -0.57 | -0.57 |
| 449.51 | -0.04 | -0.04 |