Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh-7 cells assessed as reduction in viral RNA replication a...

Basic Information

ID: ALA4046663

Type: Functional

Description: Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh-7 cells assessed as reduction in viral RNA replication after 72 hrs by luciferase reporter gene assay

Format: BAO_0000219

Organism: Hepacivirus hominis

Strain: genotype 1b Con1

Target: Hepatitis C virus(ALA379)

Document: ALA4043192

Antiviral activity against HCV genotype 1b Con1 expressing NS3 protease infected in human Huh-7 cells assessed as reduction in viral RNA replication after 72 hrs by luciferase reporter gene assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4046663

EC50

Total(42)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
260.22	-1.48	-1.48
529.46	1.66	1.66
529.46	1.66	1.66
258.23	-2.46	-2.46
626.63	0.92	0.92
545.91	1.93	1.93
276.68	-1.22	-1.22
606.03	2.00	2.00
569.96	2.00	2.00
593.96	2.72	2.72
582.98	0.78	0.78
498.88	1.25	1.25
451.80	0.88	0.88
451.80	0.88	0.88
587.99	2.95	2.95
573.97	2.56	2.56
531.89	1.54	1.54
593.96	2.72	2.72
569.96	2.00	2.00
531.89	1.54	1.54
451.80	0.88	0.88
593.96	2.72	2.72
531.89	1.54	1.54
545.91	1.93	1.93
559.94	2.32	2.32
573.97	2.56	2.56
573.97	2.56	2.56
677.11	2.76	2.76
573.97	2.56	2.56
451.80	0.88	0.88
545.91	1.93	1.93
545.91	1.93	1.93
559.94	2.32	2.32
606.03	2.00	2.00
573.97	2.56	2.56
498.88	1.25	1.25
677.11	2.76	2.76
531.89	1.54	1.54
593.96	2.72	2.72
573.97	2.56	2.56
587.99	2.95	2.95
582.98	0.78	0.78