Basic Information
ID: ALA4046783
Type: ADME
Description: Metabolic stability in human hepatic microsomes assessed as parent compound remaining at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4043199
Metabolic stability in human hepatic microsomes assessed as parent compound remaining at 1 uM after 30 mins in presence of NADPH by LC-MS/MS analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4046783
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.80 | 4.04 | 4.04 |
| 323.33 | 3.07 | 3.07 |
| 353.35 | 3.08 | 3.08 |
| 341.32 | 3.21 | 3.21 |
| 357.77 | 3.73 | 3.73 |
| 366.33 | 3.08 | 3.08 |
| 375.76 | 3.87 | 3.87 |
| 341.32 | 3.21 | 3.21 |
| 374.78 | 3.53 | 3.53 |
| 341.32 | 3.21 | 3.21 |