Basic Information
ID: ALA4046791
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4043199
Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4046791
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.33 | 3.07 | 3.07 |
| 375.76 | 3.87 | 3.87 |
| 374.78 | 3.53 | 3.53 |
| 341.32 | 3.21 | 3.21 |