ID: ALA4046966
Type: Binding
Description: Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4043212
Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control: 1
Bioactivity
Activity Types for Assay ALA4046966
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
588.56 | 1.34 | 1.34 |
387.44 | 6.00 | 6.00 |
405.50 | 6.19 | 6.19 |
396.88 | 6.78 | 6.78 |