Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled p...

Basic Information

ID: ALA4046966

Type: Binding

Description: Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control

Format: BAO_0000357

Organism: Homo sapiens

Target:  DNA topoisomerase II alpha(ALA1806)

Document:  ALA4043212

Inhibition of human topoisomerase-2 alpha assessed as reduction in conversion of super coiled plasmid DNA to relaxed DNA at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
588.561.341.34
387.446.006.00
405.506.196.19
396.886.786.78