Basic Information
ID: ALA4046968
Type: Binding
Description: Potency index, ratio of inhibitory activity of etoposide to test compound for inhibition of human topoisomerase-2 alpha at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase II alpha(ALA1806)
Document: ALA4043212
Potency index, ratio of inhibitory activity of etoposide to test compound for inhibition of human topoisomerase-2 alpha at 100 uM using supercoiled pBR322 DNA as substrate after 30 mins by ethidium bromide staining based agarose gel electrophoresis method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4046968
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 405.50 | 6.19 | 6.19 |