Basic Information
ID: ALA4047134
Type: Binding
Description: Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.5 uM after 6 hrs by Western blot analysis relative to NSC126405
Format: BAO_0000219
Organism: Homo sapiens
Target: DEP domain-containing mTOR-interacting protein(ALA4105866)
Document: ALA4043223
Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.5 uM after 6 hrs by Western blot analysis relative to NSC126405: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4047134
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 196.25 | 2.40 | 2.40 |
| 322.02 | 5.15 | 5.15 |
| 440.11 | 5.72 | 5.72 |
| 338.02 | 4.86 | 4.86 |
| 308.00 | 4.85 | 4.85 |
| 210.24 | 2.36 | 2.36 |
| 384.09 | 6.57 | 6.57 |
| 194.24 | 2.38 | 2.38 |
| 332.01 | 4.26 | 4.26 |
| 263.94 | 3.37 | 3.37 |
| 316.02 | 3.90 | 3.90 |
| 325.99 | 4.99 | 4.99 |
| 273.93 | 2.87 | 2.87 |
| 288.33 | 4.67 | 4.67 |
| 294.35 | 3.94 | 3.94 |
| 375.99 | 5.87 | 5.87 |
| 376.88 | 6.15 | 6.15 |
| 476.09 | 6.00 | 6.00 |
| 336.00 | 4.16 | 4.16 |
| 259.95 | 3.30 | 3.30 |
| 325.99 | 4.99 | 4.99 |
| 325.99 | 4.99 | 4.99 |
| 313.96 | 3.09 | 3.09 |
| 288.01 | 4.12 | 4.12 |
| 342.01 | 3.87 | 3.87 |
| 232.88 | 3.21 | 3.21 |
| 468.17 | 6.33 | 6.33 |
| 314.04 | 4.66 | 4.66 |