Basic Information
ID: ALA4047164
Type: ADME
Description: Apparent permeability of the compound in MDCK cells expressing human MRDR1 at 3 uM after 60 mins in presence of P-gp inhibitor GF120918A by LC-MS/MS analysis
Organism: Canis lupus familiaris
Cell type: MDCK
Activity Charts
Bioactivity
Activity Types for Assay ALA4047164
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.54 | 3.46 | 3.46 |
| 481.08 | 4.21 | 4.21 |
| 417.51 | 3.58 | 3.58 |
| 481.57 | 3.05 | 3.05 |
| 488.63 | 4.08 | 4.08 |
| 528.70 | 4.69 | 4.69 |
| 395.53 | 3.42 | 3.42 |
| 463.58 | 2.21 | 2.21 |
| 396.43 | 3.57 | 3.57 |
| 360.46 | 4.47 | 4.47 |
| 523.63 | 1.23 | 1.23 |
| 577.66 | 3.34 | 3.34 |
| 541.61 | 3.79 | 3.79 |
| 495.60 | 3.44 | 3.44 |
| 467.59 | 3.39 | 3.39 |
| 453.56 | 3.13 | 3.13 |
| 475.55 | 3.43 | 3.43 |
| 534.70 | 2.58 | 2.58 |
| 506.65 | 1.80 | 1.80 |