Basic Information
ID: ALA4047400
Type: Binding
Description: Displacement of [125I]-L-691831 from human FLAP expressed in Sf9 cell membranes after 2 hrs by Topcount method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4047400
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.35 | 2.16 | 2.16 |
| 373.42 | 2.98 | 2.98 |
| 417.47 | 3.09 | 3.09 |
| 431.50 | 3.21 | 3.21 |
| 337.39 | 2.04 | 2.04 |
| 418.46 | 2.48 | 2.48 |
| 432.49 | 2.56 | 2.56 |
| 432.49 | 2.61 | 2.61 |
| 416.45 | 2.41 | 2.41 |
| 388.44 | 2.86 | 2.86 |
| 363.43 | 2.57 | 2.57 |
| 374.41 | 2.67 | 2.67 |
| 374.41 | 2.37 | 2.37 |
| 374.41 | 2.67 | 2.67 |
| 374.41 | 2.37 | 2.37 |
| 487.57 | 3.09 | 3.09 |
| 473.54 | 2.75 | 2.75 |
| 427.47 | 3.10 | 3.10 |
| 393.45 | 1.93 | 1.93 |
| 462.56 | 2.63 | 2.63 |
| 461.53 | 2.42 | 2.42 |
| 461.57 | 2.88 | 2.88 |
| 378.44 | 2.15 | 2.15 |
| 463.59 | 2.72 | 2.72 |
| 415.46 | 2.85 | 2.85 |
| 406.49 | 2.79 | 2.79 |
| 415.46 | 3.01 | 3.01 |
| 459.51 | 2.17 | 2.17 |
| 448.53 | 3.10 | 3.10 |
| 376.46 | 3.57 | 3.57 |
| 406.49 | 2.93 | 2.93 |
| 390.45 | 2.87 | 2.87 |
| 388.44 | 2.62 | 2.62 |
| 422.53 | 3.42 | 3.42 |
| 412.46 | 3.36 | 3.36 |
| 406.49 | 2.79 | 2.79 |
| 336.40 | 2.64 | 2.64 |
| 392.46 | 2.40 | 2.40 |
| 430.47 | 2.65 | 2.65 |
| 364.41 | 1.76 | 1.76 |
| 486.58 | 3.70 | 3.70 |
| 413.45 | 2.75 | 2.75 |
| 472.55 | 3.36 | 3.36 |
| 377.45 | 1.99 | 1.99 |
| 373.42 | 3.28 | 3.28 |
| 416.49 | 3.33 | 3.33 |
| 446.52 | 2.85 | 2.85 |
| 392.46 | 2.54 | 2.54 |
| 434.54 | 3.97 | 3.97 |
| 407.48 | 2.18 | 2.18 |
| 432.49 | 2.90 | 2.90 |
| 421.51 | 2.57 | 2.57 |
| 408.51 | 3.03 | 3.03 |
| 362.44 | 3.18 | 3.18 |
| 431.50 | 3.17 | 3.17 |
| 413.45 | 2.61 | 2.61 |
| 420.52 | 3.18 | 3.18 |