Basic Information
ID: ALA4047404
Type: ADME
Description: Stability in human liver microsomes at 1 uM pretreated for 10 mins followed by NADPH addition after 60 mins by LC/MS analysis relative to hepatic blood flow
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4047404
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 373.42 | 2.98 | 2.98 |
| 431.50 | 3.21 | 3.21 |
| 432.49 | 2.61 | 2.61 |
| 416.45 | 2.41 | 2.41 |
| 374.41 | 2.37 | 2.37 |
| 462.56 | 2.63 | 2.63 |
| 461.53 | 2.42 | 2.42 |
| 461.57 | 2.88 | 2.88 |
| 378.44 | 2.15 | 2.15 |
| 463.59 | 2.72 | 2.72 |
| 415.46 | 2.85 | 2.85 |
| 406.49 | 2.79 | 2.79 |
| 415.46 | 3.01 | 3.01 |
| 459.51 | 2.17 | 2.17 |
| 448.53 | 3.10 | 3.10 |
| 406.49 | 2.93 | 2.93 |
| 390.45 | 2.87 | 2.87 |
| 388.44 | 2.62 | 2.62 |
| 422.53 | 3.42 | 3.42 |
| 406.49 | 2.79 | 2.79 |
| 392.46 | 2.40 | 2.40 |
| 430.47 | 2.65 | 2.65 |
| 364.41 | 1.76 | 1.76 |
| 377.45 | 1.99 | 1.99 |
| 416.49 | 3.33 | 3.33 |
| 446.52 | 2.85 | 2.85 |
| 392.46 | 2.54 | 2.54 |
| 434.54 | 3.97 | 3.97 |
| 432.49 | 2.90 | 2.90 |
| 408.51 | 3.03 | 3.03 |
| 413.45 | 2.61 | 2.61 |
| 420.52 | 3.18 | 3.18 |