Basic Information
ID: ALA4047447
Type: Binding
Description: Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin peptide as substrate measured after 30 mins by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Lysine-specific histone demethylase 1(ALA6136)
Document: ALA4043241
Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin peptide as substrate measured after 30 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4047447
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 4.58 | 4.58 |
| 418.54 | 3.58 | 3.58 |
| 441.58 | 3.92 | 3.92 |
| 375.47 | 3.50 | 3.50 |
| 401.55 | 4.34 | 4.34 |
| 427.55 | 3.67 | 3.67 |
| 455.61 | 4.18 | 4.18 |
| 387.53 | 4.09 | 4.09 |
| 401.55 | 4.48 | 4.48 |
| 404.51 | 3.06 | 3.06 |
| 359.47 | 3.80 | 3.80 |
| 387.53 | 3.97 | 3.97 |
| 415.58 | 4.60 | 4.60 |
| 435.53 | 3.93 | 3.93 |
| 373.50 | 3.58 | 3.58 |
| 401.55 | 4.48 | 4.48 |
| 427.55 | 3.67 | 3.67 |
| 359.47 | 3.80 | 3.80 |
| 387.53 | 3.97 | 3.97 |