Basic Information
ID: ALA4047824
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate pretreated for 15 mins followed by NADPH addition measured after 8 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4047824
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.31 | 3.50 | 3.50 |
| 367.32 | 3.45 | 3.45 |
| 368.30 | 2.84 | 2.84 |
| 367.32 | 3.45 | 3.45 |
| 363.35 | 3.62 | 3.62 |
| 386.29 | 2.98 | 2.98 |
| 351.30 | 2.10 | 2.10 |
| 363.35 | 3.62 | 3.62 |
| 368.30 | 2.84 | 2.84 |
| 375.32 | 2.57 | 2.57 |
| 386.29 | 2.98 | 2.98 |
| 379.35 | 3.32 | 3.32 |