Inhibition of full-length recombinant human DAT expressed in CHOK1 cells assessed as reduction in [3H]dopamine uptake pretreated for 20 mins followed ...

Basic Information

ID: ALA4047847

Type: ADME

Description: Inhibition of full-length recombinant human DAT expressed in CHOK1 cells assessed as reduction in [3H]dopamine uptake pretreated for 20 mins followed by [3H]dopamine addition measured after 10 mins by scintillation counting method

Format: BAO_0000219

Organism: Homo sapiens

Target: Dopamine transporter(ALA238)

Document: ALA4043265

Inhibition of full-length recombinant human DAT expressed in CHOK1 cells assessed as reduction in [3H]dopamine uptake pretreated for 20 mins followed by [3H]dopamine addition measured after 10 mins by scintillation counting method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4047847

IC50

Total(7)

Parent Molecular Weight	ALogP	Polar Surface Area
238.33	2.85	2.85
368.30	2.84	2.84
386.29	2.98	2.98
351.30	2.10	2.10
368.30	2.84	2.84
375.32	2.57	2.57
386.29	2.98	2.98

Parent Molecular Weight

ALogP

Polar Surface Area

238.33

2.85

368.30

2.84

386.29

2.98

351.30

2.10