Assay Report Card

Basic Information

ID: ALA4047934

Type: ADME

Description: Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate assessed as residual activity at 5 uM after 20 mins by HPLC analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
511.531.111.11
470.831.111.11
506.471.101.10
522.491.671.67
523.471.921.92
463.801.531.53
463.801.531.53
523.471.921.92
537.502.392.39
463.801.531.53
868.811.611.61