Basic Information
ID: ALA4047935
Type: ADME
Description: Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate assessed as residual activity at 5 uM after 20 mins by HPLC analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4047935
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.47 | 1.10 | 1.10 |
| 522.49 | 1.67 | 1.67 |
| 523.47 | 1.92 | 1.92 |
| 463.80 | 1.53 | 1.53 |
| 523.47 | 1.92 | 1.92 |
| 537.50 | 2.39 | 2.39 |
| 463.80 | 1.53 | 1.53 |
| 868.81 | 1.61 | 1.61 |