Basic Information
ID: ALA4048641
Type: Binding
Description: Inhibition of MNK1/2 in human HCT116 cells assessed as decrease in eIF4E phosphorylation at Ser209 after 2 hrs by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4048641
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.31 | 1.13 | 1.13 |
| 485.33 | 3.50 | 3.50 |
| 376.37 | 1.88 | 1.88 |
| 320.74 | 1.05 | 1.05 |
| 271.28 | 0.82 | 0.82 |
| 340.39 | 1.63 | 1.63 |
| 428.88 | 2.74 | 2.74 |
| 360.81 | 1.98 | 1.98 |
| 305.73 | 1.47 | 1.47 |
| 254.29 | 2.20 | 2.20 |
| 354.37 | 1.17 | 1.17 |
| 395.25 | 2.63 | 2.63 |
| 289.27 | 0.96 | 0.96 |
| 331.38 | 2.81 | 2.81 |
| 346.78 | 1.59 | 1.59 |
| 240.27 | 2.02 | 2.02 |
| 309.33 | 1.81 | 1.81 |