Basic Information
ID: ALA4049157
Type: ADME
Description: Drug metabolism in cynomolgus monkey liver microsomes assessed as 5-(Hydroxymethyl)-7-(3-(hydroxymethyl)-1-methyl-5-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-4-yl)-2-methylimidazo-[5,1-f ][1,2,4]triazin-4(3H)-one formation at 20 uM after 1.2 hrs by UHPLC-UV-HRMS method
Organism: Macaca fascicularis
Tissue: Liver
Subcellular Fraction: microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4049157
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.37 | 2.82 | 2.82 |