Basic Information
ID: ALA4049251
Type: Binding
Description: Inhibition of PDE4 (unknown origin) expressed in HEK293 cells co-expressing PM-AKAR3 assessed as increase in cAMP levels at 1 uM by FRET assay relative to rolipram
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4043306
Inhibition of PDE4 (unknown origin) expressed in HEK293 cells co-expressing PM-AKAR3 assessed as increase in cAMP levels at 1 uM by FRET assay relative to rolipram: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4049251
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.32 | 3.14 | 3.14 |
| 375.29 | 4.25 | 4.25 |
| 327.28 | 3.78 | 3.78 |
| 411.40 | 5.10 | 5.10 |
| 416.44 | 3.98 | 3.98 |
| 380.37 | 3.99 | 3.99 |
| 393.41 | 4.97 | 4.97 |
| 400.44 | 3.61 | 3.61 |
| 372.39 | 2.98 | 2.98 |
| 309.29 | 3.64 | 3.64 |
| 358.40 | 3.45 | 3.45 |
| 366.34 | 3.60 | 3.60 |
| 339.31 | 3.65 | 3.65 |
| 316.32 | 2.33 | 2.33 |
| 366.34 | 3.60 | 3.60 |
| 423.43 | 4.97 | 4.97 |
| 344.38 | 3.06 | 3.06 |
| 393.41 | 4.97 | 4.97 |
| 386.41 | 3.37 | 3.37 |
| 380.37 | 3.91 | 3.91 |
| 339.44 | 4.26 | 4.26 |