Basic Information
ID: ALA4049702
Type: Binding
Description: Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76V-GFP assessed as reduction in UbG76V-GFP degradation rate by fluorescence microscopic method
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4049702
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 632.81 | 3.71 | 3.71 |
| 674.76 | 6.90 | 6.90 |
| 588.72 | 6.23 | 6.23 |
| 540.59 | 6.06 | 6.06 |
| 722.74 | 9.48 | 9.48 |
| 329.45 | 3.39 | 3.39 |
| 572.72 | 7.00 | 7.00 |
| 628.83 | 6.44 | 6.44 |
| 406.49 | 3.78 | 3.78 |
| 622.72 | 7.72 | 7.72 |
| 816.92 | 4.76 | 4.76 |
| 588.72 | 6.23 | 6.23 |
| 630.81 | 5.23 | 5.23 |
| 550.62 | 3.39 | 3.39 |
| 754.98 | 8.27 | 8.27 |
| 299.36 | 2.37 | 2.37 |
| 574.73 | 5.40 | 5.40 |
| 600.78 | 6.36 | 6.36 |
| 586.74 | 7.44 | 7.44 |
| 566.66 | 6.63 | 6.63 |
| 646.79 | 7.46 | 7.46 |
| 594.72 | 6.71 | 6.71 |
| 626.85 | 7.65 | 7.65 |
| 628.83 | 6.44 | 6.44 |
| 434.55 | 4.30 | 4.30 |
| 588.72 | 6.23 | 6.23 |
| 598.80 | 7.57 | 7.57 |