Assay Report Card

Basic Information

ID: ALA4049704

Type: Binding

Description: Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated for 1 hr followed by substrate addition measured after 80 mins by fluorescence polarization assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
145.161.941.94
144.181.821.82
143.192.542.54
632.813.713.71
674.766.906.90
588.726.236.23
175.262.832.83
540.596.066.06
408.464.984.98
586.747.447.44
722.749.489.48
162.221.921.92
329.453.393.39
572.727.007.00
628.836.446.44
408.464.984.98
161.232.522.52
161.232.522.52
175.262.962.96
436.515.165.16
406.493.783.78
598.807.577.57
622.727.727.72
816.924.764.76
175.262.832.83
588.726.236.23
175.262.832.83
630.815.235.23
436.515.165.16
550.623.393.39
598.807.577.57
754.988.278.27
299.362.372.37
574.735.405.40
436.515.165.16
408.464.984.98
600.786.366.36
160.243.133.13
586.747.447.44
566.666.636.63
646.797.467.46
566.666.636.63
594.726.716.71
626.857.657.65
175.262.832.83
175.262.832.83
628.836.446.44
434.554.304.30
588.726.236.23
598.807.577.57