Basic Information
ID: ALA4050205
Type: Binding
Description: Inhibition of Mps1/TTK in human CAL51 cells assessed as reduction in centrosome amplification during S-phase by measuring decrease in cells with more than four centrioles incubated for 24 hrs followed by BrdU incorporation during last 4 hrs of incubation
Format: BAO_0000219
Organism: Homo sapiens
Target: Dual specificity protein kinase TTK(ALA3983)
Document: ALA4049399
Inhibition of Mps1/TTK in human CAL51 cells assessed as reduction in centrosome amplification during S-phase by measuring decrease in cells with more than four centrioles incubated for 24 hrs followed by BrdU incorporation during last 4 hrs of incubation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4050205
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.66 | 4.60 | 4.60 |
| 422.53 | 4.29 | 4.29 |