Basic Information
ID: ALA4050207
Type: Binding
Description: Inhibition of Mps1/TTK in human MDA-MB-468 cells assessed as reduction in centriole assembly during S-phase by measuring increase in BrdU positive cells with two centrioles at 10 uM incubated for 24 hrs followed by BrdU incorporation during last 4 hrs of incubation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4050207
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.67 | 5.20 | 5.20 |
| 452.56 | 3.47 | 3.47 |
| 536.66 | 4.60 | 4.60 |
| 422.53 | 4.29 | 4.29 |
| 636.78 | 5.85 | 5.85 |