Basic Information
ID: ALA4050223
Type: Binding
Description: Inhibition of Mps1/TTK in human MDA-MB-468 cells assessed as reduction in centrosome amplification during S-phase by measuring decrease in cells with more than four centrioles at 10 uM incubated for 24 hrs followed by BrdU incorporation during last 4 hrs of incubation
Format: BAO_0000219
Organism: Homo sapiens
Target: Dual specificity protein kinase TTK(ALA3983)
Document: ALA4049399
Inhibition of Mps1/TTK in human MDA-MB-468 cells assessed as reduction in centrosome amplification during S-phase by measuring decrease in cells with more than four centrioles at 10 uM incubated for 24 hrs followed by BrdU incorporation during last 4 hrs of incubation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4050223
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 535.67 | 5.20 | 5.20 |
| 452.56 | 3.47 | 3.47 |
| 636.78 | 5.85 | 5.85 |