Basic Information
ID: ALA4050229
Type: ADME
Description: Drug metabolism in human liver cytosol assessed as as AOX-mediated 3-(difluoro(quinolin-7-yl)methyl)-6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7(8H)-one oxidative metabolite formation by measuring amount of compound oxidized at 10 uM after 30 mins by UPLC/Q-TOF MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Cytosol
Target: Aldehyde oxidase(ALA3257)
Document: ALA4049400
Drug metabolism in human liver cytosol assessed as as AOX-mediated 3-(difluoro(quinolin-7-yl)methyl)-6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7(8H)-one oxidative metabolite formation by measuring amount of compound oxidized at 10 uM after 30 mins by UPLC/Q-TOF MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4050229
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.34 | 4.01 | 4.01 |