ID: ALA4050234
Type: ADME
Description: Drug metabolism in human liver cytosol assessed as AOX-mediated 2-fluoro-N-methyl-4-(3-oxo-7-(quinolin-7-ylmethyl)-3,4-dihydroimidazo[1,2-b][1,2,4]triazin-2-yl)benzamide metabolite formation by measuring LC-MS peak area of the metabolite at 10 uM after 30 min by UPLC/Q-TOF MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Cytosol
Target: Aldehyde oxidase(ALA3257)
Document: ALA4049400
Drug metabolism in human liver cytosol assessed as AOX-mediated 2-fluoro-N-methyl-4-(3-oxo-7-(quinolin-7-ylmethyl)-3,4-dihydroimidazo[1,2-b][1,2,4]triazin-2-yl)benzamide metabolite formation by measuring LC-MS peak area of the metabolite at 10 uM after 30 min by UPLC/Q-TOF MS analysis: 1
Bioactivity
Activity Types for Assay ALA4050234
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
428.43 | 2.72 | 2.72 |