Drug metabolism in human liver cytosol assessed as AOX-mediated 2-fluoro-N-methyl-4-(3-oxo-7-(quinolin-7-ylmethyl)-3,4-dihydroimidazo[1,2-b][1,2,4]tri...

ID: ALA4050239

Type: ADME

Description: Drug metabolism in human liver cytosol assessed as AOX-mediated 2-fluoro-N-methyl-4-(3-oxo-7-(quinolin-7-ylmethyl)-3,4-dihydroimidazo[1,2-b][1,2,4]triazin-2-yl)benzamide metabolite formation by measuring LC-MS peak area of the metabolite at 10 uM after 30 mins in presence of menadione by UPLC/Q-TOF MS analysis

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Cytosol

Target:  Aldehyde oxidase(ALA3257)

Document:  ALA4049400

Drug metabolism in human liver cytosol assessed as AOX-mediated 2-fluoro-N-methyl-4-(3-oxo-7-(quinolin-7-ylmethyl)-3,4-dihydroimidazo[1,2-b][1,2,4]triazin-2-yl)benzamide metabolite formation by measuring LC-MS peak area of the metabolite at 10 uM after 30 mins in presence of menadione by UPLC/Q-TOF MS analysis: 1