Basic Information
ID: ALA4050425
Type: Binding
Description: Inhibition of Tel-fused EGFR T790M mutant (unknown origin) expressed in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CellTiter-Glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4050425
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.51 | 4.22 | 4.22 |
| 499.62 | 4.51 | 4.51 |
| 426.48 | 3.83 | 3.83 |
| 492.97 | 3.39 | 3.39 |
| 469.55 | 3.71 | 3.71 |
| 489.97 | 4.05 | 4.05 |
| 491.98 | 4.28 | 4.28 |
| 506.97 | 4.80 | 4.80 |
| 541.41 | 5.45 | 5.45 |
| 485.55 | 3.41 | 3.41 |
| 473.51 | 3.54 | 3.54 |
| 454.53 | 4.00 | 4.00 |
| 543.03 | 4.54 | 4.54 |
| 488.98 | 4.66 | 4.66 |
| 567.07 | 4.06 | 4.06 |
| 483.58 | 4.02 | 4.02 |
| 506.97 | 4.80 | 4.80 |
| 547.06 | 3.98 | 3.98 |
| 480.53 | 3.27 | 3.27 |
| 524.96 | 4.94 | 4.94 |
| 521.00 | 5.23 | 5.23 |
| 514.95 | 5.56 | 5.56 |
| 506.97 | 4.80 | 4.80 |