Assay Report Card

Basic Information

ID: ALA4050533

Type: Functional

Description: Antitumor activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant xenografted in nu/nu mouse assessed as tumor growth inhibition at 100 mg/kg/day administered via oral gavage after 21 days relative to vehicle-control

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
489.974.054.05