Assay Report Card

Basic Information

ID: ALA4050537

Type: Functional

Description: In vivo inhibition of EGFR exon 19 deletion mutant phosphorylation at Y1068 in human PC9 cells xenografted in nu/nu mouse at 25 to 100 mg/kg/day administered via oral gavage after 21 days by Western blot method

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
489.974.054.05