Assay Report Card

Basic Information

ID: ALA4050538

Type: Functional

Description: Antitumor activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant xenografted in nu/nu mouse assessed as reduction in tumor cell proliferation administered via oral gavage after 21 days by Ki-67 staining based immunohistochemistry method

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
489.974.054.05