Basic Information
ID: ALA4050581
Type: Binding
Description: Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins followed by 4alphaPDD stimulation measured for 5 mins by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4050581
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.90 | 4.39 | 4.39 |
| 471.52 | 5.46 | 5.46 |
| 572.64 | 5.32 | 5.32 |
| 539.09 | 4.96 | 4.96 |
| 560.63 | 5.18 | 5.18 |
| 534.67 | 3.80 | 3.80 |
| 560.63 | 5.18 | 5.18 |
| 583.54 | 5.07 | 5.07 |
| 547.67 | 3.40 | 3.40 |
| 572.64 | 5.32 | 5.32 |
| 576.63 | 4.15 | 4.15 |
| 573.63 | 4.72 | 4.72 |
| 548.65 | 4.00 | 4.00 |
| 570.67 | 6.53 | 6.53 |
| 602.67 | 5.07 | 5.07 |
| 522.64 | 4.44 | 4.44 |
| 556.58 | 3.69 | 3.69 |
| 582.74 | 3.71 | 3.71 |
| 555.59 | 4.29 | 4.29 |
| 560.63 | 5.18 | 5.18 |
| 571.65 | 5.93 | 5.93 |
| 572.64 | 5.32 | 5.32 |
| 555.59 | 4.29 | 4.29 |
| 546.60 | 4.79 | 4.79 |
| 572.64 | 5.32 | 5.32 |
| 560.63 | 5.18 | 5.18 |
| 504.65 | 4.31 | 4.31 |
| 529.66 | 4.18 | 4.18 |
| 614.60 | 5.72 | 5.72 |
| 588.64 | 4.56 | 4.56 |
| 572.64 | 5.32 | 5.32 |