Basic Information
ID: ALA4050583
Type: Binding
Description: Antagonist activity at recombinant rat TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins followed by 4alphaPDD stimulation measured for 5 mins by FLIPR assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4050583
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 471.52 | 5.46 | 5.46 |
| 572.64 | 5.32 | 5.32 |
| 560.63 | 5.18 | 5.18 |
| 560.63 | 5.18 | 5.18 |
| 602.67 | 5.07 | 5.07 |
| 556.58 | 3.69 | 3.69 |
| 555.59 | 4.29 | 4.29 |
| 560.63 | 5.18 | 5.18 |
| 572.64 | 5.32 | 5.32 |
| 614.60 | 5.72 | 5.72 |
| 588.64 | 4.56 | 4.56 |