Basic Information
ID: ALA4050701
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as half life for metabolic turnover at 0.1 to 10 uM preincubated for 60 mins in presence of NADPH measured up to 60 mins by mass spectroscopic analysis
Format: BAO_0000019
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: microsome
Target: Liver(ALA613642)
Document: ALA4049411
Metabolic stability in rat liver microsomes assessed as half life for metabolic turnover at 0.1 to 10 uM preincubated for 60 mins in presence of NADPH measured up to 60 mins by mass spectroscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4050701
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.43 | 5.02 | 5.02 |
| 358.36 | 4.33 | 4.33 |
| 372.32 | 4.85 | 4.85 |
| 354.40 | 4.77 | 4.77 |
| 372.39 | 4.72 | 4.72 |
| 376.35 | 4.63 | 4.63 |
| 372.39 | 4.72 | 4.72 |
| 368.43 | 5.02 | 5.02 |
| 390.38 | 5.02 | 5.02 |
| 368.43 | 5.02 | 5.02 |
| 336.34 | 4.57 | 4.57 |