Basic Information
ID: ALA4051359
Type: Binding
Description: Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated RSK levels
Format: BAO_0000219
Organism: Homo sapiens
Target: MAP kinase ERK2(ALA4040)
Document: ALA4049432
Inhibition of ERK2 in human A375 cells harboring BRAF V600E mutant assessed as decrease in phosphorylated RSK levels: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4051359
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.87 | 3.16 | 3.16 |
| 433.34 | 4.67 | 4.67 |
| 587.69 | 3.69 | 3.69 |
| 381.44 | 1.98 | 1.98 |
| 381.44 | 1.60 | 1.60 |
| 395.47 | 2.29 | 2.29 |
| 418.50 | 2.96 | 2.96 |
| 327.39 | 1.69 | 1.69 |
| 442.53 | 3.48 | 3.48 |
| 313.36 | 1.28 | 1.28 |
| 367.41 | 1.59 | 1.59 |
| 371.44 | 1.71 | 1.71 |
| 442.53 | 3.48 | 3.48 |
| 433.51 | 2.79 | 2.79 |
| 327.39 | 1.36 | 1.36 |
| 313.36 | 1.35 | 1.35 |
| 385.47 | 1.72 | 1.72 |
| 428.50 | 3.17 | 3.17 |
| 395.47 | 2.22 | 2.22 |
| 395.47 | 2.29 | 2.29 |
| 381.44 | 1.98 | 1.98 |
| 381.44 | 1.83 | 1.83 |
| 485.95 | 3.59 | 3.59 |
| 403.49 | 3.26 | 3.26 |
| 395.47 | 2.22 | 2.22 |
| 485.95 | 3.59 | 3.59 |
| 428.50 | 3.09 | 3.09 |
| 417.51 | 3.27 | 3.27 |
| 403.49 | 2.25 | 2.25 |