Basic Information
ID: ALA4051432
Type: Binding
Description: Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Kynurenine 3-monooxygenase(ALA2145)
Document: ALA4049435
Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4051432
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.76 | 2.65 | 2.65 |
| 468.89 | 3.30 | 3.30 |
| 271.66 | 1.73 | 1.73 |
| 481.93 | 4.34 | 4.34 |
| 418.87 | 2.92 | 2.92 |
| 497.93 | 3.08 | 3.08 |
| 436.85 | 1.75 | 1.75 |
| 483.91 | 3.26 | 3.26 |
| 502.35 | 4.69 | 4.69 |
| 484.89 | 2.65 | 2.65 |
| 406.82 | 2.12 | 2.12 |
| 497.93 | 3.57 | 3.57 |
| 466.92 | 3.70 | 3.70 |
| 473.87 | 2.85 | 2.85 |
| 497.93 | 3.57 | 3.57 |
| 483.91 | 3.26 | 3.26 |
| 376.79 | 2.03 | 2.03 |
| 469.88 | 2.70 | 2.70 |
| 501.90 | 3.40 | 3.40 |
| 432.86 | 2.51 | 2.51 |
| 475.93 | 2.20 | 2.20 |
| 361.79 | 3.74 | 3.74 |
| 390.82 | 2.29 | 2.29 |
| 378.84 | 3.73 | 3.73 |
| 344.80 | 4.30 | 4.30 |
| 518.35 | 3.91 | 3.91 |
| 446.88 | 2.90 | 2.90 |
| 276.07 | 2.38 | 2.38 |
| 418.83 | 2.26 | 2.26 |
| 497.93 | 3.57 | 3.57 |
| 364.76 | 4.17 | 4.17 |
| 467.91 | 4.03 | 4.03 |
| 483.91 | 3.26 | 3.26 |